Mechanisms of Hepatitis B Virus Resistance Development
نویسندگان
چکیده
منابع مشابه
Mechanisms of hepatitis B virus resistance development.
Hepatitis B virus (HBV) resistance to nucleos(t)ide analogue (NA) therapy is essentially structure specific, with each NA falling within three main structural groups. Resistance to each of these is characterized by specific mutations in the reverse transcriptase domains of the HBV polymerase, and may be associated with compensatory mutations which can increase replication. HBV polymerase is con...
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ژورنال
عنوان ژورنال: Intervirology
سال: 2014
ISSN: 0300-5526,1423-0100
DOI: 10.1159/000360940